Hepatic sinusoidal-obstruction syndrome and busulfan-induced lung injury in a post-autologous stem cell transplant recipient

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Hepatic Sinusoidal-obstruction Syndrome and Busulfan-induced Lung Injury in a Post-autologous Stem Cell Transplant Recipient.

Veno-occlusive disease of the liver is mostly encountered as a complication of hematopoietic stem cell transplantation with myeloablative regimens with an incidence estimated to be 13.7%. It is clinically characterized by tender hepatomegaly, jaundice, weight gain and ascites. Strong clinical suspicion and an early recognition of clinical signs are essential to establish the diagnosis and insti...

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Hepatic sinusoidal obstruction syndrome in patients undergoing hematopoietic stem cell transplant.

PURPOSE/OBJECTIVES To provide a comprehensive review of hepatic sinusoidal obstruction syndrome (HSOS) in patients receiving a hematopoietic stem cell transplant and to describe the implications for nursing care. DATA SOURCES Published research articles, reviews, case reports, and books. DATA SYNTHESIS Disagreement exists regarding the precise cause of HSOS. Prevention and treatment strateg...

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Hepatic sinusoidal obstruction syndrome following hematopoietic stem cell transplantation.

J.m., a 43-year-old man with acute myelogenous leukemia with a monosomy 7 cytogenetic abnormality, received an allogeneic hematopoietic stem cell transplantation (HscT) from his human leukocyte antigen– matched brother. Past treatments included idarubicin and cytarabine induction therapy followed by a cycle of high-dose cytarabine. J.m. was in complete remission prior to the HscT. The condition...

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Disseminated Fusarium infection in autologous stem cell transplant recipient.

Disseminated infection by Fusarium is a rare, frequently lethal condition in severely immunocompromised patients, including bone marrow transplant recipients. However, autologous bone marrow transplant recipients are not expected to be at high risk to develop fusariosis. We report a rare case of lethal disseminated Fusarium infection in an autologous bone marrow transplant recipient during pre-...

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Hepatosplenic mucormycosis post autologous stem cell transplant

Mucormycosis is a life threatening fungal infection and remains an important cause of morbidity and mortality in immunocompromised patients after hematopoietic stem cell transplant. We report here a case of hepatosplenic mucormycosis in a patient after autologous stem cell transplant. A young man with anaplastic large cell lymphoma underwent autologous hematopoietic stem cell transplant after a...

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ژورنال

عنوان ژورنال: Indian Pediatrics

سال: 2017

ISSN: 0019-6061,0974-7559

DOI: 10.1007/s13312-017-1172-5